RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 - https://t.co/PEWiBbPMW2
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
Important info on why no in vivo activity vs SARS-CoV-2 “all of the 23 cationic amphiphilic drugs tested, including hydroxychloroquine, azithromycin, amiodarone, and four others already in clinical trials, phospholipidosis was monotonically correlated wi
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 https://t.co/trddFodls3
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @fraser_lab: Paper of the year! Seriously... read this! So much $ and time wasted through an artifactual signal in drug repurposing.
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 https://t.co/3Ol6e5l4B6
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
Super important work from the CCC (coolest Canadian chemist)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
Paper of the year! Seriously... read this! So much $ and time wasted through an artifactual signal in drug repurposing.
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 https://t.co/iVCkclm51S
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
Incredibly insightful paper.
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
Really cool finding… drug repurposing is hard!
RT @zenbrainest: Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co…
Congratulations on this massive, fantastic work Tia Tummino, @BShoichet lab, and collaborators. Very cool stuff!
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @BShoichet: This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
Must read for all pharmacologists, chemical biologists and drug-hunters! A pesky artifact finally revealed!! https://t.co/v5zLdezKaB
This paper now out in Science https://t.co/4TQBSx6Mml. Key observations: (1/N)
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 | Science https://t.co/9wfdOy5kCR
RT @ScienceMagazine: As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through p…
As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through phospholipidosis are unlikely to be effective in vivo. Screening out such drugs may allow a focus on drugs with better clinical potential.
Scary reading. Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 https://t.co/iKrMAqUbMZ
As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through phospholipidosis are unlikely to be effective in vivo. Screening out such drugs may allow a focus on drugs with better clinical potential.